MeDIP (Methylated DNA immuniprecipitation) is an enrichment technique that uses antibodies specific to 5mC (methylated cytocines) to isolate methylated DNA fragments.
In brief, the DNA is denaturated to separate the double-strnaded DNA into single stranded DNA. This process enables the methyl-group to be accessible. Then, monoclonal or polyclonal antibodies …
Here is an update of the open projects (green) and closed projects during the last 6 months (sept 2019 to feb 2020). This was a hard time. We were still in the process of catching up with projects (march-sept 2019) when 2 engineers left the platform and only one replaced …
read moreManaging multiple projects is a hard task. Within the Biomics Platform, we manage about 200 projects a year. Within the SALSA group, we deal with various daily tasks and issues: analysing genomic data, helping users in solving their sequencing problems, working with the wetlab, managing our submission website, etc. Overall …
read moreHere is an example of a Pacbio Assembly we did recently on a bacterial genome. Following the generation of the data at the Platform, the SALSA group applied some standard and less standard analysis to produce this 1-contig assembly. This type of analysis is now quite standard within the platform …
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