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#6388 : Analysis of spontaneous kanamycin resistance
Topics: Genomics (Illumina)
Origin: IP
Project type: Service

Name of Applicant: Zeynep Baharoglu
Date of application: 25-11-2021
Unit: Bacterial Genome Plasticity
Location: duclaux
Phone: 01 86 46 73 84
@ Mail: baharogl@pasteur.fr
@ PI-Mail: mazel@pasteur.fr

Project context and summary:

While studying conditions leading to kanamycin tolerance and resistance development in E. coli, we have found that growth in certain conditions lead to high frequency of apparition of spontaneous kanamycin resistant colonies. We will sequence geneomic DNA of these colonies in paralel to the wild type parental strain in order to detect mutations leading to such high resistance levels.


Related team publications:
doi: 10.1371/journal.pgen.1009748
doi: 10.1016/j.isci.2021.103128
10.3390/cells10113227
Service Delivery
Manager: marc.monot@pasteur.fr
Status: Quotation sent


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