Topics: Others
Origin: IP
Project type: Service
Name of Applicant: Julien Gaillard
Date of application: 05-05-2020
Unit: Biology of Infection
Location: Duclaux/Fourneaux-RH-19
Phone: 3369
@ Mail: julien.gaillard@pasteur.fr
@ PI-Mail: marc.lecuit@pasteur.fr
Project context and summary: Listeria monocytogenes (Lm) is a human foodborne pathogen that crosses the intestinal barrier, disseminates systemically, replicates in liver and spleen and reaches the central nervous system (CNS) and fetal-placental unit.
Infection dynamic’s between organs is unknown and is the topic of this project.
Related team publications:1. M. Lecuit et al., A transgenic model for listeriosis: role of internalin in crossing the intestinal barrier. Science. 292, 1722–1725 (2001).
2. O. Disson et al., Conjugated action of two species-specific invasion proteins for fetoplacental listeriosis. Nature. 455, 1114–1118 (2008).
Manager: marc.monot@pasteur.frStatus: Closed