The primary focus of our lab is to understand interactions between Aedes aegypti mosquitoes and the arboviruses they transmit to humans (i.e. dengue viruses, Zika virus, Chikungunya virus). In particular, we aim to understand the molecular mechanisms underlying natural resistance or susceptibility of field-derived mosquito colonies to dengue viruses, using approaches combining single-cell omics and CRISPR-Cas9 genome editing tools.
Related team publications: