Project

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#19580 : Diversity of Yellow fever virus populations in Aedes aegypti saliva
Topics: Genomics (Illumina)
Origin: IP
Project type: Expertise

Name of Applicant: Anna-Bella FAILLOUX
Date of application: 01-04-2025
Unit: Arboviruses and Insect Vectors
Location: Nicolle – RDC
Phone: 0786603527
@ Mail: anna-bella.failloux@pasteur.fr

Project context and summary:

Yellow fever virus is mainly transmitted by the mosquito Aedes aegypti in urban settings causing outbreaks. The anthropo-zoophilic mosquito, Aedes albopcitus and the sylvatic mosquito Aedes malayensis may play a role in selecting viral populations more adapted to infect non human primates and therefore, to initiate a wild cycle. Our project aims at defining the diversity of viral populations in saliva excreted by the 3 different mosquito species.


Related team publications:
Gabiane G, Bohers C, Mousson L, Obadia T, Dinglasan RR, Vazeille M, Dauga C, Viglietta M, Yébakima A, Vega-Rúa A, Gutiérrez Bugallo G, Gélvez Ramírez RM, Sonor F, Etienne M, Duclovel-Pame N, Blateau A, Smith-Ravin J, De Lamballerie X, Failloux AB. Evaluating vector competence for Yellow fever in the Caribbean. Nat Commun. 2024 Feb 9;15(1):1236. doi: 10.1038/s41467-024-45116-2
Lataillade LG, Vazeille M, Obadia T, Madec Y, Mousson L, Kamgang B, Chen CH, Failloux AB*, Yen PS*. Risk of yellow fever virus transmission in the Asia-Pacific region. Nat Commun. 2020 Nov 16;11(1):5801. doi: 10.1038/s41467-020-19625-9
Amraoui F, Pain A, Piorkowski G, Vazeille M, Couto-Lima D, de Lamballerie X, Lourenço-de-Oliveira R, Failloux AB. Experimental Adaptation of the Yellow Fever Virus to the Mosquito Aedes albopictus and Potential risk of urban epidemics in Brazil, South America. Sci Rep. 2018 Sep 25;8(1):14337. doi: 10.1038/s41598-018-32198-4
Service Delivery
Manager: iakov.vitrenko@pasteur.fr
Status: Quotation sent


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