Project

Go Back to Project List
#18342 : Chikungunya virus infection of skeletal muscles
Topics: Transcriptomics (Illumina)
Origin: IP
Project type: Service

Name of Applicant: Thibaud GOUPIL
Date of application: 04-06-2024
Unit: Biology of Infection
Location: Duclaux – aile Fourneau- RDC haut – bureau 16B
Phone: 0658810128
@ Mail: thibaud.goupil@pasteur.fr
@ PI-Mail: marc.lecuit@pasteur.fr

Project context and summary:

Chikungunya virus (CHIKV), the most prevalent mosquito-borne alphavirus, causes severe arthralgia and myalgia that can persist for years and have a significant impact on health and quality of life. Increasing evidence suggests that skeletal muscle infection plays a critical role in the development of CHIKV disease. The Four-and-a-Half-LIM-protein-1 (FHL1) is a key host factor required for CHIKV replication and associated muscle pathogenesis. This protein is highly expressed in CHIKV-target cells such as fibroblasts or muscle cells.


Related team publications:
Service Delivery
Manager: marc.monot@pasteur.fr
Status: Closed


Go Back to Project List