Project

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#17393 : Studying growth and antibiotic response in E. coli
Topics: Transcriptomics (Illumina)
Origin: Academic
Project type: Service

Name of Applicant: Imane El Meouche
Date of application: 19-09-2023
Unit: Other
Location: Faculte de Medecine, 16 rue Henri Bichat
Phone: 0763915384
@ Mail: imane.el-meouche@inserm.fr

Project context and summary:

we propose to study antibiotic response in natural isolates in various media. We focus on pathogenic extraintestinal Escherichia coli strains and started by determining their resistance and tolerance profiles. Antibiotic tolerance enables a population to survive antibiotic treatment for a longer duration without a resistance mechanism. We selected few strains and after determining their growth and and antibiotic response profiles we would like to have insights into the genetics mechanisms behind their higher survival.


Related team publications:
I. El Meouche and M. Dunlop. Heterogeneity in efflux pump expression predisposes antibiotic resistant cells to mutation. Science. doi: 10.1126/science.aar7981. November 2018.
Service Delivery
Manager: marc.monot@pasteur.fr
Status: Libraries


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