Topics: Genomics (Illumina)
Origin: RIIP
Project type: Collaboration
Name of Applicant: Alia Benkahla
Date of application: 06-02-2023
Unit: Other
Location: Institut Pasteur de Tunis
Phone: +216 22 938439
@ Mail: alia.benkahla@pasteur.tn
@ PI-Mail: sinda.zarrouk@pasteur.tn
Project context and summary: Cobra bites are a medical emergency whose frequency is a public health problem in Tunisia. The development of genomic tools for a better understanding of bite-induced diseases is currently hampered by the absence of a genomic sequence of the Tunisian cobra. The New Generation Sequencing techniques and the availability of the assembly of the Indian cobra genome now make it possible to work towards obtaining such a sequence. As part of this project we propose to sequence, assemble and annotate the genome of the Tunisian cobra Naja haje haje.
This project will be realized in the frame of the partnership between Biomics (consulting, kit shipment and sequencing) and IPTomics (prep and control of Libraries).
Related team publications:Choudhury A, Aron S, Botigué LR, Sengupta D, Botha G, Bensellak T, Wells G, Kumuthini J, Shriner D, Fakim YJ, Ghoorah AW, Dareng E, Odia T, Falola O, Adebiyi E, Hazelhurst S, Mazandu G, Nyangiri OA, Mbiyavanga M, Benkahla A, Kassim SK, Mulder N, Adebamowo SN, Chimusa ER, Muzny D, Metcalf G, Gibbs RA; TrypanoGEN Research Group, Rotimi C, Ramsay M; H3Africa Consortium, Adeyemo AA, Lombard Z, Hanchard NA. (2020) High-depth African genomes inform human migration and health. Nature. 586(7831):741-748. doi: 10.1038/s41586-020-2859-7. PMID: 33116287
Bussotti G, Benkahla A, Jeddi F, Souiaï O, Aoun K, Späth GF, and A Bouratbine. (2020) Nuclear and mitochondrial genome sequencing of North-African Leishmania infantum isolates from cured and relapsed visceral leishmaniasis patients reveals variations correlating with geography and phenotype. Microb Genom. 6(10). doi: 10.1099/mgen.0.000444. PMID: 32975503
Oukkache N, R El Jaoudi, N Ghalim, F Chgoury, B Bouhaouala, N El Mdaghri, JM Sabatier. (2014) Evaluation of the lethal potency of scorpion and snake venoms and comparison between intraperitoneal and intravenous injection routes. PMID: 24926799 PMCID: PMC4073134 DOI: 10.3390/toxins6061873
Manager: imene.najjar@pasteur.frStatus: Closed
