Topics: Metagenomics (16s)
Origin: Academic
Project type: Service
Name of Applicant: Garance Coquant
Date of application: 06-10-2020
Unit: Other
Location: 27, rue Chaligny 75012 Paris
Phone: 0140011461
@ Mail: garance.coquant@sorbonne-universite.fr
@ PI-Mail: pseksik@gmail.com
Project context and summary: Bacteria can communicate thanks to Quorum Sensing, using small molecules called Acyl-Homoserine Lactones (AHL). We are aiming at caracterising the impact of natural and synthetic AHLs on gut microbiota composition. We administrated AHLs to mice in order to analyse their impact on bacterial populations in the feaces.
Related team publications:Landman, C., Grill, J. P., Mallet, J. M., Marteau, P., Humbert, L., Le Balc’h, E., … & Beaugerie, L. (2018). Inter-kingdom effect on epithelial cells of the N-Acyl homoserine lactone 3-oxo-C12: 2, a major quorum-sensing molecule from gut microbiota. PloS one, 13(8), e0202587.
Coquant, G., Grill, J. P., & Seksik, P. (2020). Impact of N-Acyl-Homoserine Lactones, Quorum Sensing Molecules, on Gut Immunity. Frontiers in Immunology, 11.
Manager: georges.haustant@pasteur.frStatus: Closed
