Topics: Genomics (Illumina)
Origin: Extern
Project type: Service
Name of Applicant: Frédérique Le Roux
Date of application: 02-06-2020
Unit: Other
Location: Roscoff
Phone: 07 83 01 28 90
@ Mail: frederique.le-roux@sb-roscoff.fr
Project context and summary: How phages shape bacterial diversity is the subject of major hypotheses (i.e. kill the winner, red queen)? These hypotheses have been explored experimentaly in the laboratory. How these hypotheses apply in nature, however, remains to be explored. We conducted a time series sampling in an oyster farm and isolated vibrios that are pathogenic for oysters as well as their infecting phages. We have characterized the host range of these phages and now will characterize their genetic diversity.
Related team publications:2- Rubio T, Oyanedel-Trigo D, Labreuche Y, Toulza E, Luo X, Bruto M, Chaparro C, Torres Bejar M, de Lorgeril J, Haffner P, Vidal-Dupiol J, Lagorce A, Petton B, Mitta G, Jacq A, Le Roux F*, Charrière G* and Destoumieux-Garzón D1*. Species-specific mechanisms of cytotoxicity towards immune cells determine the successful outcome of Vibrio infections. Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14238-14247.(*co-correspondence)
3- Bruto M, Labreuche Y, James A, Piel D, Chenivesse S, Petton B, Polz MF, Le Roux F. Ancestral gene acquisition as the key to virulence potential in environmental Vibrio populations. ISME J. 2018 Dec;12(12):2954-2966
5- Labreuche Y, Chenivesse S, Jeudy A, Le Panse S, Boulo V, Ansquer D, Pagès S, Givaudan A, Czjzek M, Le Roux F. Nigritoxin is a bacterial toxin for crustaceans and insects. Nat Commun. 2017 Nov 1;8(1):1248
Manager: marc.monot@pasteur.frStatus: Closed
