Project

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#22068 : Variabilité de la biosynthèse des oxylipines immunomodulatrices et son impact sur la sévérité de la maladie de COVID-19 (VARIANCE)
Topics:
Origin:
Project type: Development

Name of Applicant: François Le Guerroué
Date of application: 22-10-2026
Unit: Single Cell Platform
Location: 26-01-03C
Phone:
@ Mail: francois.le-guerroue@pasteur.fr
@ PI-Mail: milena.hasan@pasteur.fr

Project context and summary:

The inflammatory response is a protective immune response against infection and/or injury. For that, the host produces a wide range of inflammatory mediators including cytokines but also oxylipins. These include hundreds of lipid mediators produced from the oxygenation of polyunsaturated fatty acids (PUFA) through complex enzymatic pathways.
The strategic objectives here is to assess how genes are regulated by the oxylipin response of stimulated Whole Blood cells.


Related team publications:
Service Delivery
Status: New


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