The inflammatory response is a protective immune response against infection and/or injury. For that, the host produces a wide range of inflammatory mediators including cytokines but also oxylipins. These include hundreds of lipid mediators produced from the oxygenation of polyunsaturated fatty acids (PUFA) through complex enzymatic pathways.
The strategic objectives here is to assess how genes are regulated by the oxylipin response of stimulated Whole Blood cells.