HTLV is the causal agent of a neurological disorder named HAM/TSP. IT is the consequence of both infiltration of infected cells in the central nervous system and consecutive alteration of the CSF composition;
In order to understand the mechanisms of neuroinflammation and neurodedegeneration, we aim at studying the impact of the supernatant of infected lymphocytes and CSF from diseased partients on the transcriptomic of iPSC derives neurons, astrocytes and microglial cells in this context