Topics: Transcriptomics (Illumina)
Origin: IP
Project type: Service
Name of Applicant: Borrel Guillaume
Date of application: 13-02-2024
Unit: Evolutionary Biology of the Microbial Cell
Location: 02 – 01 – 01A
Phone: +331 44 38 92 91
@ Mail: guillaume.borrel@pasteur.fr
Project context and summary: Methanogenic archaea are present in the gut of many animals, including human, where their role and ecology remain elusive. Methanogens are dependent on bacteria to obtain growth nutrients and bacteria can change their metabolic output in response to methanogen activity. We aim to study the influence of methanogens and fermentative bacteria on each other by determining changes in gene expression level when they are cultured alone or together.
Related team publications:Thomas CM, Desmond-Le Quemener E, Gribaldo S, and Borrel G. Factors shaping the abundance and diversity of the gut archaeome across the animal kingdom. Nature Communications (2022) 13:3358. https://doi.org/10.1038/s41467-022-31038-4
Thomas CM, Taib N, Gribaldo S, Borrel G. Comparative genomic analysis of Methanimicrococcus blatticola provides insights into host-adaptation in archaea and the evolution of methanogenesis. ISME Communications (2021) 1:47. https://doi.org/10.1038/s43705-021-00050-y
Borrel G, Brugère J-F, Gribaldo S, Schmitz RA, Moissl-Eichinger C. The host-associated archaeome. Nature Review Microbiology (2020) 18:622–636. https://doi.org/10.1038/s41579-020-0407-y
Manager: elodie.turc@pasteur.frStatus: Sequencing
