Topics: Genomics (Illumina)
Origin: IP
Project type: Service
Name of Applicant: Hana Kammoun
Date of application: 06-03-2023
Unit: Biology of Infection
Location: Duclaux, RDH, 11
Phone: 0684431753
@ Mail: hana.kammoun-chaari@pasteur.fr
@ PI-Mail: marc.lecuit@pasteur.fr
Project context and summary: The gastrointestinal tract is exposed to many commensal microbes (the microbiota), food antigens, and enteropathogens. Therefore, the single layer of epithelial cells constituting the intestinal barrier is challenged continuously and interacts with mucosal myeloid cells to orchestrate an appropriate host response to these external stimuli.
Related team publications:1. Nikitas, G., et al., Transcytosis of Listeria monocytogenes across the intestinal barrier upon specific targeting of goblet cell accessible E-cadherin. J Exp Med, 2011. 208(11): p. 2263-772.
2. Gessain, G., et al., PI3-kinase activation is critical for host barrier permissiveness to Listeria monocytogenes. J Exp Med, 2015. 212(2): p. 165-83
3. Lecuit, M., et al., A transgenic model for listeriosis: role of internalin in crossing the intestinal barrier. Science, 2001. 292(5522): p. 1722-5
Manager: elodie.turc@pasteur.frStatus: Closed
