Institut Pasteur
Biomics
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ERC SyG Analysis of the transcriptome, methylome and chromatin status of zebrafish neural stem cells

Status: Pending

Project ID: B19035

Owner: Laure BALLY-CUIF

Unit: Zebrafish Neurogenetics

Experiment type: To be determined

Location: Monod - 5th floor - Rm 08

Description

Neural stem cells in the zebrafish telencephalon are transcriptomically heterogeneous. We aim to reconstruct their individual molecular trajectories, inferred from the single-cell analysis of chromatin states and methylation marks. The latter will include classical CpG methylation reads and Dcm methylation marks induced as "time stamps" in gene bodies of transcribed genes. The datasets will be generated via the production of scNMT libraries.

Submitted: 2024-11-23 12:47 · Last updated: 2024-11-23 12:47